
Thermo Fisher Scientific Caspase 10 Polyclonal Antibody
Caspase 10 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 사용 가능. 합성 펩타이드(505-521 aa) 기반 면역원으로 제작. 액상 형태이며 -20°C 보관. 세포 사멸 연구용으로 적합.
- 카탈로그번호
- PA112507
- 판매단위
- pk
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Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 505–521 of human FLICE2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1070982 |
Product Specific Information
A suggested positive control for this product is HeLa whole cell lysate.
Target Information
This gene encodes a protein that belongs to the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits (large and small), which dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7 and is itself processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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