Thermo Fisher Scientific SMURF2 Recombinant Superclonal Antibody (4HCLC)

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Rat, Rabbit, and Mouse.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine the sensitivity of polyclonal antibodies with the specificity and reproducibility of monoclonal antibodies.
Each Superclonal™ antibody consists of a defined mixture of recombinant monoclonal antibodies, ensuring consistent lot-to-lot performance and eliminating biological variability.
Formerly called “Recombinant polyclonal antibody,” this product is now rebranded as “Recombinant Superclonal™ antibody.” The physical product and performance remain unchanged.

Target Information

SMURF2 is an E3 ubiquitin-protein ligase that transfers ubiquitin from an E2 enzyme to target substrates. It interacts with SMAD1, SMAD2, and SMAD7 to promote their ubiquitination and degradation.
SMURF2 enhances SMAD7 inhibitory activity and reduces SMAD2 transcriptional activity. Coexpression with SMAD1 decreases SMAD1 protein levels and slightly reduces SMAD2 levels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.