Thermo Fisher Scientific SMURF2 Recombinant Superclonal Antibody (4HCLC)
인간 SMURF2 단백질(aa 151-242)을 인식하는 Recombinant Superclonal™ 항체로, WB 및 ICC/IF에 적합합니다. 다중 클론 특성을 통해 높은 감도와 일관된 재현성을 제공합니다. Protein A 정제, PBS 저장, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 4HCLC |
| Immunogen | Protein corresponding to Human SMURF2 (aa 151–242) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633162 |
Product Specific Information
This antibody is predicted to react with Rat, Rabbit, and Mouse.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine the sensitivity of polyclonal antibodies with the specificity and reproducibility of monoclonal antibodies.
Each Superclonal™ antibody consists of a defined mixture of recombinant monoclonal antibodies, ensuring consistent lot-to-lot performance and eliminating biological variability.
Formerly called “Recombinant polyclonal antibody,” this product is now rebranded as “Recombinant Superclonal™ antibody.” The physical product and performance remain unchanged.
Target Information
SMURF2 is an E3 ubiquitin-protein ligase that transfers ubiquitin from an E2 enzyme to target substrates. It interacts with SMAD1, SMAD2, and SMAD7 to promote their ubiquitination and degradation.
SMURF2 enhances SMAD7 inhibitory activity and reduces SMAD2 transcriptional activity. Coexpression with SMAD1 decreases SMAD1 protein levels and slightly reduces SMAD2 levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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