Thermo Fisher Scientific AMPK beta-1 Recombinant Superclonal Antibody (22HCLC)

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Cat, and Bovine.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
These antibodies recognize multiple epitope sites on the target, providing higher detection sensitivity for low-abundance targets.
Each lot contains a defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability seen in traditional polyclonal production.

Note: Formerly called “Recombinant Polyclonal Antibody”, now rebranded as “Recombinant Superclonal™ Antibody”. Product performance remains unchanged.

Target Information

AMPK beta-1 is a regulatory subunit of the AMP-activated protein kinase (AMPK), a heterotrimeric enzyme composed of alpha (catalytic), beta, and gamma (non-catalytic) subunits.
AMPK acts as a key energy sensor regulating cellular metabolism. Upon activation under metabolic stress, it phosphorylates and inactivates key enzymes such as acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), controlling fatty acid and cholesterol biosynthesis.
The beta-1 subunit may positively regulate AMPK activity and serve as an adaptor mediating complex assembly. Its myristoylation and phosphorylation influence AMPK localization and activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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