Thermo Fisher Scientific EAAT2 (GLT-1) (extracellular) Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
• Ships as a lyophilized powder at room temperature.
• Upon arrival, store at -20°C.
• Reconstituted solution can be stored at 4°C for up to 1 week.
• For longer periods, store aliquots at -20°C.
• Avoid multiple freeze-thaw cycles.
• Centrifuge antibody preparations before use (10,000 × g, 5 min).

Target Information

Excitatory amino acid transporter 2 (EAAT2) is a membrane-bound solute transporter responsible for clearing the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Proper glutamate clearance prevents neuronal damage from excessive receptor activation. Mutations or decreased expression of EAAT2 are associated with amyotrophic lateral sclerosis (ALS). Alternatively spliced transcript variants have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.