Thermo Fisher Scientific CCR8 Polyclonal Antibody
CCR8 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot, IHC, Flow cytometry, ELISA에 사용 가능. 고농도(1 mg/mL) 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. 인간 K562 세포 및 비장 조직에 양성 대조로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:125 |
| Flow Cytometry (Flow) | 2–6 µL for 10⁶ cells in 100 µL |
| ELISA | 1:50,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues V(12)TDYYY PDIFSSPCDAELIQTNGKLC(36) of human CCR8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_557995 |
Product Specific Information
- Recommended positive controls: Human K562 cells (ICC) or human spleen (IHC-P).
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
CCR8 encodes a member of the beta chemokine receptor family, predicted to be a seven-transmembrane G protein-coupled receptor. Chemokines and their receptors regulate migration of immune cells to inflammatory sites.
This receptor is preferentially expressed in the thymus, and ligands include I-309, TARC, and MIP1β.
CCR8 is involved in monocyte chemotaxis, thymic cell apoptosis, and positioning of activated T cells in lymphoid tissues.
Expression is found in spleen, thymus, NK cells, monocytes, T cells, and at lower levels in peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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