Thermo Fisher Scientific CCR3 Polyclonal Antibody
Thermo Fisher Scientific의 CCR3 Polyclonal Antibody는 인간 CCR3 단백질을 인식하는 goat IgG 기반 항체입니다. WB, IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:300 |
| Immunocytochemistry (ICC/IF) | 1:300 |
| ELISA | 1:30,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues CVETF GTT SYY DDV GLL CEK ADT RALMA of human CCR3 (aa 8–34) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 10 mM potassium phosphate with 0.1% BSA, 140 mM NaCl |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_557983 |
Product Specific Information
- Recommended positive controls: Human peripheral blood cells
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. CCR3 transduces a signal by increasing intracellular calcium ion levels and serves as an alternative co-receptor with CD4 for HIV-1 infection.
Chemokines play essential roles in inflammation and are critical for recruiting effector immune cells to infection sites. They activate leukocytes via G protein-coupled receptors. Chemokine receptors are mainly categorized into CXCR and CCR groups.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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