Thermo Fisher Scientific CCR6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:125

-

Flow Cytometry (Flow)

2-6 µL for 10^6 cells in 100 µL

-

ELISA (ELISA)

1:37,500

-

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues Y(18) F V S V N T S Y Y S V D S E M L L C S L Q E V R Q F S R(46) of human CCR6. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCR6,uniProtId:P51684-1,ncbiNodeId:9606,antigenRange:18-46,antigenLength:374,antigenImageFileName:PA1-21615_CCR6_P51684-1_Goat.svg,antigenImageFileNamePDP:PA1-21615_CCR6_P51684-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.01M potassium phosphate with 0.14M NaCl, 0.1% BSA

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2072799

Product Specific Information

Recommended positive controls: Human spleen or peripheral blood.

This antibody does not detect mouse CCR6.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.