Thermo Fisher Scientific CCR6 Polyclonal Antibody
CCR6 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체로, WB, IHC, Flow cytometry, ELISA에 사용 가능. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:250 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:125 | - |
| Flow Cytometry (Flow) | 2–6 µL for 10⁶ cells in 100 µL | - |
| ELISA | 1:37,500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues Y(18) F V S V N T S Y Y S V D S E M L L C S L Q E V R Q F S R(46) of human CCR6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M potassium phosphate with 0.14M NaCl, 0.1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2072799 |
Product Specific Information
- Recommended positive controls: Human spleen or peripheral blood
- This antibody does not detect mouse CCR6
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
CCR6 is a member of the beta chemokine receptor family, predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. Its ligand is macrophage inflammatory protein 3 alpha (MIP-3α). CCR6 plays a role in B-lineage maturation and antigen-driven B-cell differentiation and may regulate migration and recruitment of dendritic and T cells during inflammatory and immune responses. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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