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Thermo Fisher Scientific XPF Monoclonal Antibody (UMAB20), UltraMAB
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Thermo Fisher Scientific XPF Monoclonal Antibody (UMAB20), UltraMAB

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XPF 단백질을 인식하는 UMAB20 클론의 마우스 단일클론 항체로, Western blot, IHC, ICC/IF, ChIP 등 다양한 응용 가능. 인간, 마우스, 랫, 개에 반응하며, 액상 형태로 제공. DNA 손상 복구 관련 연구에 적합.

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마지막 업데이트 2025. 08. 04. 오후 06:27
Thermo Fisher Scientific UM500020 XPF Monoclonal Antibody (UMAB20), UltraMAB 100 ul pk판매 단위 pk ·
재고 확인 필요
770,300원VAT 포함 847,330원
Thermo Fisher Scientific UM570020 XPF Monoclonal Antibody (UMAB20), UltraMAB 30 ul pk판매 단위 pk ·
재고 확인 필요
301,100원VAT 포함 331,210원

Thermo Fisher Scientific · Thermo Fisher Scientific XPF Monoclonal Antibody (UMAB20), UltraMAB

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:500
Immunocytochemistry (ICC/IF) 1:100
ChIP assay (ChIP) Assay-dependent

Product Specifications

Specification Description
Species Reactivity Dog, Human, Mouse, Rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Clone UMAB20
Immunogen Full-length human recombinant XPF protein produced in HEK293 cells
Conjugate Unconjugated
Form Liquid
Concentration 0.5–1.0 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions –20°C, Avoid freeze/thaw cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

The structure-specific ERCC1/XPF endonuclease complex is involved in the repair of two distinct types of DNA lesions:

  • Nucleotide Excision Repair (NER) for UV-induced lesions and bulky chemical adducts
  • Recombination Repair for genotoxic interstrand cross-links

In mammalian cells, XPG cleaves the 3′ side of the lesion, while ERCC1/XPF makes the 5′ incision.
ERCC1/XPF also likely participates in processing partially repaired recombination intermediates.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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