Thermo Fisher Scientific CNR2 Polyclonal Antibody
Rabbit polyclonal antibody against human CNR2 (CB2) for IHC (Paraffin) applications. High specificity and affinity-purified. Cross-reactive with several mammalian species. Supplied as liquid, 1 mg/mL in PBS with 0.1% sodium azide. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–10 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from internal region of human CNR2 / CB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550825 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla (100%)
- Monkey, Marmoset, Elephant (95%)
- Gibbon, Bovine (89%)
- Horse (84%)
Target Information
Cannabinoids exert their physiological effects through two G protein-coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both receptors inhibit adenylyl cyclase and stimulate MAPK (mitogen-activated protein kinase).
CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannabinol and related ligands likely exert psychoactive effects by inhibiting presynaptic N- and P/Q-type calcium channels.
CB2 functions primarily in the immune system, though it may also be present in the central nervous system, including the retina.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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