Thermo Fisher Scientific CRHR1 Polyclonal Antibody
Human 및 Rat 반응성 Rabbit Polyclonal CRHR1 항체로 스트레스 반응 및 불안 관련 연구에 적합. IHC(P)에서 13 µg/mL로 검증됨. 항원 친화 크로마토그래피로 정제된 액상 형태. 장기 보관 시 -20°C 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 13 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from N-terminal extracellular domain of human CRF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550827 |
Product Specific Information
- This antibody is not recommended for use in ICC applications.
- Percent identity with other species by BLAST analysis:
- Human, Monkey (100%)
- Marmoset (94%)
- Rat (82%)
Target Information
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing. CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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