Thermo Fisher Scientific CLCN7 Monoclonal Antibody (4A3)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
LRLKDFRDAY PRFPPIQSIH VSQDERECTM DLSEFMNPSP YTVPQEASLP RVFKLFRALG LRHLVVVDNR NQVVGLVTRK DLARYRLGKR GLEELSLAQT

Target Information

The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7 (CLCN7).
Defects in this gene are associated with:

• Osteopetrosis autosomal recessive type 4 (OPTB4), also known as infantile malignant osteopetrosis type 2
• Autosomal dominant osteopetrosis type 2 (OPTA2), also called Albers-Schonberg disease or marble disease

Osteopetrosis is a rare genetic disorder characterized by abnormally dense bone due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, typically occurring in adolescence or adulthood.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.