Thermo Fisher Scientific FNTB Polyclonal Antibody
Human FNTB 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합하며 고순도 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관되며 연구용으로 사용.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 250–300 of Human FNTB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719151 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Eukaryotic cells contain three different types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in various proteins. These posttranslational modifications enable membrane localization of proteins lacking a transmembrane domain.
CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins ending in the CAAX box, where C is cysteine, A is usually an aliphatic amino acid, and X is typically methionine or serine.
The FNTB gene encodes the beta subunit of CAAX farnesyltransferase and is located at 14q23–q24 in the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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