Thermo Fisher Scientific Lambda Light Chain (B-Cell Marker) Monoclonal Antibody (LcN-2), CF 488

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1:50-1:100

-

Flow Cytometry (Flow)

5 µL/10^6 cells

-

Immunomicroscopy (IM)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

LcN-2

Immunogen

Purified human IgG if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Lambda light chain,uniProtId:P0CG04-1,ncbiNodeId:9606,antigenRange:1-106,antigenLength:106,antigenImageFileName:3535-MSM3-CF488-100T_Lambda_light_chain_P0CG04-1_House_mouse.svg,antigenImageFileNamePDP:3535-MSM3-CF488-100T_Lambda_light_chain_P0CG04-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

CF® 488 CF® 488 CF® 488

View additional formats

• Unconjugated
• Request custom conjugation

Excitation/Emission Max

488/515 nm

Form

Liquid

Concentration

100 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin`s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.