
Thermo Fisher Scientific CD39 Monoclonal Antibody (24DMS1), Super Bright 600, eBioscience
Mouse CD39 단백질을 인식하는 24DMS1 클론의 Rat IgG2b 단일클론 항체로, Super Bright 600 형광체가 결합된 제품입니다. Flow Cytometry에 최적화되어 있으며, 염증 조절 연구 및 Treg 세포 분석에 활용 가능합니다. 405 nm Excitation, 600 nm Emission 특성을 가집니다.
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Thermo Fisher Scientific CD39 Monoclonal Antibody (24DMS1), Super Bright 600, eBioscience™
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1 µg/test
Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rat / IgG2b, kappa |
| Recommended Isotype Control | Rat IgG2b kappa Isotype Control (eB149/10H5), Super Bright™ 600, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 24DMS1 |
| Conjugate | Super Bright™ 600 |
| Excitation/Emission Max | 414 / 601 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2717037 |
Additional Formats
- Unconjugated
- Alexa Fluor 700
- Brilliant UV 805
- eFluor 660
- Functional Grade
- PE
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 702
- Request custom conjugation
Product Specific Information
The 24DMS1 monoclonal antibody reacts with mouse CD39 (NTPDaseI), an enzyme that converts nucleoside tri- and diphosphates into nucleoside monophosphates, thereby removing toxic extracellular ATP and ADP. CD39 plays a key role in inflammation suppression and platelet activation control. It is expressed on B cells, Langerhans cells, monocytes, and a subset of CD4+ CD25+FoxP3+ Treg cells.
Treg cells from CD39-deficient mice show impaired suppressive properties.
This antibody is validated for flow cytometric analysis of mouse splenocytes, recommended ≤1 µg/test (100 µL final volume).
Super Bright 600 is a tandem dye excited at 405 nm and emits at 600 nm. Recommended filter: 610/20 bandpass.
When using multiple Super Bright dyes, use Super Bright Complete Staining Buffer (Product # SB-4401) to minimize non-specific interactions.
Light Sensitivity: Protect from light to prevent photo-induced oxidation.
Fixation: Samples can be stored in IC Fixation Buffer (Product # 00-8222) or 1-step Fix/Lyse Solution (Product # 00-5333) for up to 3 days at 4°C in the dark.
Excitation: 405 nm
Emission: 600 nm
Laser: Violet Laser
Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company.
Target Information
CD39 is a 70–100 kDa cell surface antigen expressed on peripheral blood B cells, monocytes, T cell clones, and weakly on granulocytes. It possesses ecto-ATPase activity and is induced on T cells and increased on B cells as a late activation antigen.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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