Thermo Fisher Scientific RAB11FIP1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Recommended positive controls: HepG2, HCT116
• Predicted reactivity: Mouse (88%), Rat (87%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein.
By interacting with Rab GTPases, Rab11-FIP1 is involved in endosomal recycling and may play a role in controlling membrane trafficking along the phagocytic pathway and during phagocytosis.
Localized to the recycling endosome, cytoplasmic membrane, and phagosome membranes, Rab11-FIP1 is expressed as five isoforms produced by alternative splicing.
Isoform two, the most highly expressed, is found in brain, lung, testis, small intestine, spleen, and heart. It forms homooligomers and interacts with Rab 4A, Rab 11A, Rab 11B, and Rab 25.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(원본에 포함된 이미지는 아래에 배치됩니다.)