Thermo Fisher Scientific RAB11FIP1 Polyclonal Antibody
Rabbit polyclonal antibody against Human RAB11FIP1 for WB and IHC applications. Recognizes Rab11-FIP1 involved in endosomal recycling. Supplied as liquid, 0.74 mg/mL, unconjugated. Suitable for research use only.
- 카탈로그번호
- PA530892
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 81–325 of Human RAB11FIP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548366 |
Product Specific Information
- Recommended positive controls: HepG2, HCT116
- Predicted reactivity: Mouse (88%), Rat (87%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein.
By interacting with Rab GTPases, Rab11-FIP1 is involved in endosomal recycling and may play a role in controlling membrane trafficking along the phagocytic pathway and during phagocytosis.
Localized to the recycling endosome, cytoplasmic membrane, and phagosome membranes, Rab11-FIP1 is expressed as five isoforms produced by alternative splicing.
Isoform two, the most highly expressed, is found in brain, lung, testis, small intestine, spleen, and heart. It forms homooligomers and interacts with Rab 4A, Rab 11A, Rab 11B, and Rab 25.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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