Thermo Fisher Scientific COMT Polyclonal Antibody
COMT 단백질을 인식하는 Rabbit Polyclonal 항체로, 다양한 종에서 반응성을 보입니다. IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2.5–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Human, Mouse, Non-human primate, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from internal region of human COMT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550174 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bat, Bovine, Pig (100%)
Hamster, Elephant, Panda, Rabbit, Horse (93%)
Target Information
Catechol-O-methyltransferase (COMT) catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including dopamine, epinephrine, and norepinephrine.
This O-methylation represents a major degradative pathway of catecholamine neurotransmitters.
COMT also metabolizes catechol drugs used for hypertension, asthma, and Parkinson’s disease.
It exists in two forms in tissues: soluble (S-COMT) and membrane-bound (MB-COMT), differing at their N-termini.
Several transcript variants arise from alternative translation initiation sites and promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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