Thermo Fisher Scientific UBP1 Monoclonal Antibody (OTI6C7), TrueMAB
UBP1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 최적화되어 있습니다. 인간, 마우스, 랫트에서 반응하며, 동결건조 형태로 제공됩니다. PBS 버퍼에 보관하며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 47–269 of human UBP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain an antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
UBP1 acts as a transcriptional activator in a promoter context-dependent manner and modulates the placental expression of CYP11A1.
It is involved in regulation of the alpha-globin gene in erythroid cells through synergistic interaction with TFCP2.
UBP1 binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box, repressing HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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