Thermo Fisher Scientific IL-12 p70 Monoclonal Antibody (C17-8), Biotin

Thermo Fisher Scientific IL-12 p70 Monoclonal Antibody (C17-8), Biotin

Applications and Tested Dilution

Product Specifications

Additional Formats:

• Unconjugated
• Request custom conjugation

Product Specific Information

MM121B targets IL-12 in ELISA and WB applications and shows reactivity with mouse samples.
The MM121B immunogen is recombinant mouse IL-12.
MM121B detects IL-12 with a predicted molecular weight of approximately 22 kDa.

The MM121B mouse IL-12 antibody (biotinylated conjugate of clone C17-8) has been paired as a detection antibody in a sandwich ELISA with capture antibody MM120 (clone 9A5).
Typical dilutions for sandwich ELISA:

• Coating: 1 µg/mL
• Detection: 0.125–0.25 µg/mL

Biotinylated antibody MM121B (clone C17-8) and antibody MM120 (clone 9A5) have been used in combination with recombinant mouse IL-12p70 protein (SMIL12) in ELISA applications.

This antibody is produced by injecting Rat IgG-secreting hybridoma cells into the peritoneum of mice. The resulting ascites is collected and purified.

Target Information

IL-12 p70 (Interleukin-12) is a cytokine essential for immune response regulation.
Produced by dendritic cells, macrophages, and B cells in response to pathogens and tumors, IL-12 p70 stimulates interferon-gamma production and activates T cells and NK cells.
It is studied as a therapeutic target for infectious diseases, autoimmune disorders, and cancer due to its role in enhancing immune responses and modulating inflammation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.