Thermo Fisher Scientific ADM Monoclonal Antibody (OTI2A4), TrueMAB
Adrenomedullin(ADM)에 특이적인 마우스 단클론 항체로, Western blot에 최적화됨. 인간 시료 반응성. 무보존제, 동결건조 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ADM Monoclonal Antibody (OTI2A4), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–146 of human ADM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Adrenomedullin (ADM) is a vasodilator produced by contractile cells and exhibits persistent hypotensive activity. It regulates fluid and electrolyte balance and supports cardiovascular function. ADM levels are elevated in hypertensive patients and play a role in natriuresis, commonly observed in aneurysmal subarachnoid hemorrhage. ADM-induced natriuresis results from increased glomerular filtration and reduced distal tubular sodium reabsorption. ADM is found both peripherally and in the brain, where it can reduce food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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