Thermo Fisher Scientific HMG20A Monoclonal Antibody (OTI2H4), TrueMAB
HMG20A 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P) 검증 완료. 인간 시료 반응성. Lyophilized 형태로 제공되며 재구성 후 약 1 mg/mL 농도 유지. 신경 분화 및 유전자 발현 조절 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–281 of human HMG20A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
HMG20A is a chromatin-associated protein involved in neuronal differentiation. It acts as an inhibitor of HMG20B and counteracts the repressive effects of the neuronal silencer REST, promoting activation of neuronal-specific genes. HMG20A also participates in recruitment of the histone methyltransferase KMT2A/MLL1, leading to increased methylation of histone H3 lysine 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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