Thermo Fisher Scientific PMCA2 ATPase Polyclonal Antibody
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA1915 | - | Thermo Fisher Scientific PA1915 PMCA2 ATPase Polyclonal Antibody 100 ug pk | 재고문의 | pk | 716,000원 | - | 787,600원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000
View 16 publications 16 publications
Immunohistochemistry (IHC)
-
View 8 publications 8 publications
Immunohistochemistry (Paraffin) (IHC (P))
1:20-1:200
View 1 publication 1 publication
Immunohistochemistry (Frozen) (IHC (F))
1:20-1:200
View 1 publication 1 publication
Immunocytochemistry (ICC/IF)
-
View 11 publications 11 publications
ELISA (ELISA)
Assay-dependent
Immunoprecipitation (IP)
-
View 3 publications 3 publications
Functional Assay (Functional)
-
View 1 publication 1 publication
Gel Shift (GS)
-
View 1 publication 1 publication
Miscellaneous PubMed (Misc)
-
View 1 publication 1 publication
Product Specifications
Species Reactivity
Human, Pig, Rat
Published species
Chicken, Hamster, Human, Mouse, Pig, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic Peptide: T(5) N S D F Y S K N Q R N E S S(19) if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
PMCA2 ATPase,
uniProtId:
Q01814-1,
ncbiNodeId:
9606,
antigenRange:
5-19,
antigenLength:
1243,
antigenImageFileName:
PA1-915_PMCA2_ATPase_Q01814-1_Rabbit.svg,
antigenImageFileNamePDP:
PA1-915_PMCA2_ATPase_Q01814-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2243199
Product Specific Information
PA1-915 detects calcium pump of the plasma membrane 2 (PMCA2 ATPase) from human and rat and porcine tissues and cells.
PA1-915 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~127 kDa protein and an ~133 kDa protein representing PMCA2a and PMCA2b ATPase, respectively, from rat brain microsomal fractions.
PA1-915 immunizing peptide corresponds to amino acid residues 5-19 from human PMCA2 ATPase protein. This sequence is completely conserved between human and rat PMCA2 ATPase.
Target Information
The calcium pump of the plasma membrane, termed PMCA ATPase, pumps calcium from the cytosol to the extracellular space. This membrane-bound enzyme is related to a number of other ATPases including the SERCA ATPase and the sodium/K+ pump. There are four different genes encoding PMCA ATPase and studies have revealed 20 isoforms of the pump generated by alternate splicing of the primary gene products. mRNA distribution studies show that gene products 1 and 4 are transcribed in most tissues, however, products 2 and 3 are more tissue specific. Transcription of the splicing variants has also been found to be tissue specific. In the pancreas, where insulin secretion is calcium dependent, the beta cells only express the 4b isoform, however the alpha and gamma cells express both 4a and 4b isoforms. Studies have also shown that different splice variants have different affinities for calcium and calmodulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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