Thermo Fisher Scientific ATP6V0D1 Monoclonal Antibody (2G12)
ATP6V0D1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse 단일클론 항체(2G12). Western blot, IHC, ELISA 등 다양한 응용에 적합. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G12 |
| Immunogen | ATP6V0D1 (NP_004682, 238–308 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AKLFPHCGRL YPEGLAQLAR ADDYEQVKNV ADYYPEYKLL FEGAGSNPGD KTLEDRFFEH EVKLNKLAFL N
Target Information
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles.
V-ATPase dependent organelle acidification is necessary for intracellular processes such as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
V-ATPase is composed of:
- V1 domain: three A and three B subunits, two G subunits, plus C, D, E, F, and H subunits (contains ATP catalytic site)
- V0 domain: five different subunits (a, c, c’, c’’, and d)
This encoded protein is the D subunit, found ubiquitously.
Additional isoforms of many V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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