Thermo Fisher Scientific PAX8 Recombinant Mouse Monoclonal Antibody (rPAX8, 1492)
PAX8 단백질을 인식하는 재조합 마우스 모노클로날 항체로, 인간 시료에 반응합니다. IHC(파라핀) 실험에 적합하며, HEK293 세포 발현 시스템을 이용해 생산되었습니다. 고순도 Protein A/G 정제 및 PBS 버퍼로 안정화되어 연구용으로 최적화된 제품입니다.
- 카탈로그번호
- 7849-MSM5-P0
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rPAX8, 1492 |
| Immunogen | Recombinant fragment (around aa 60–261) of human PAX8 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
This gene encodes a member of the paired box family of transcription factors. Members of this gene family typically encode proteins containing a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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