Thermo Fisher Scientific PAX8 Recombinant Mouse Monoclonal Antibody (rPAX8, 1492)
PAX8 단백질을 인식하는 Thermo Fisher의 재조합 마우스 단클론 항체로, IHC(파라핀) 시료에 적합. HEK293 발현 시스템 사용, Protein A/G로 정제. 인간 PAX8(aa 60-261) 항원 기반, 4°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- 7849-MSM5-P1
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rPAX8, 1492 |
| Immunogen | Recombinant fragment (around aa 60–261) of human PAX8 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
This gene encodes a member of the paired box family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain.
This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes.
Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical follicular thyroid adenomas.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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