Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI3B8), TrueMAB
Human PTPRE 단백질에 특이적인 Mouse IgG1 단클론 항체로, Western blot, ICC/IF, Flow Cytometry에 사용 가능. Lyophilized 형태이며 PBS, trehalose buffer에 보관. 연구용으로 세포 신호전달 및 PTP 관련 연구에 적합.
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Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI3B8), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B8 |
| Immunogen | Full-length human recombinant protein of human PTPRE produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve an antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The PTPRE gene encodes a member of the protein tyrosine phosphatase (PTP) family, which regulates diverse cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Two alternatively spliced transcript variants exist:
- A receptor-type isoform with short extracellular domain, single transmembrane region, and two tandem catalytic domains.
- A nonreceptor-type isoform with a distinct hydrophilic N-terminus.
Studies in mice suggest that PTPRE plays regulatory roles in RAS-related signal transduction pathways, cytokine-induced SATA signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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