Thermo Fisher Scientific RAR gamma-1,2 Recombinant Rabbit Monoclonal Antibody (9K3Y1)
RAR gamma-1,2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. HEK293 세포에서 발현되었으며 Protein A로 정제된 고순도 항체입니다. 인간, 생쥐, 랫드 반응성이 있으며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9K3Y1 |
| Immunogen | Synthetic peptide (amino acids 1–100 of human RARG) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.03 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS (pH 7.3), 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
MATNKERLFA AGALGPGSGY PGAGFPFAFP GALRGSPPFE MLSPSFRGLG QPDLPKEMAS LSVETQSTSS EEMVPSSPSP PPPPRVYKPC FVCNDKSSGY
Target Information
Retinoic acid, a metabolite of vitamin A, is essential for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. It functions through interaction with the nuclear protein retinoic acid receptor (RAR), part of the steroid and thyroid hormone receptor superfamily.
RAR regulates gene expression by binding to specific DNA response elements. There are three major RAR subtypes: alpha, beta, and gamma.
RAR gamma has two isoforms:
- RAR gamma-1: predominantly expressed in skin
- RAR gamma-2: found early in embryogenesis and in embryonal carcinoma cells
RAR gamma is also known as RARD, and the gene encoding RAR gamma-1 is NR1B3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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