Thermo Fisher Scientific OX40 (CD134) Recombinant Rabbit Monoclonal Antibody (RM313)
OX40(CD134) 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체로 높은 특이성과 민감도를 제공. WB 및 IHC(P) 적용 가능. HEK293 발현 시스템 기반, Protein A 정제, PBS/BSA/glycerol 버퍼에 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM313 |
| Immunogen | A peptide corresponding to the C-terminus of human OX40 (CD134) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2744949 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
OX40 is a protein receptor found on the surface of T cells, which play a crucial role in immune response. When activated, OX40 promotes T cell proliferation and survival, enhancing immune defense against cancer and infections.
OX40 agonists have shown potential in immunotherapy for cancer, improving efficacy of treatments such as chemotherapy and checkpoint inhibitors, and may also have applications in autoimmune diseases and allergies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: MA5-27895_OX40_CD134_P43489-1_Rabbit.svg, MA5-27895_OX40_CD134_P43489-1_Rabbit_PDP.jpeg)
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