
Thermo Fisher Scientific LIMK2 Polyclonal Antibody
LIMK2 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간·마우스·랫트 반응성 확인. 장기 보관 시 -20°C에서 안정적이며, 연구용으로 사용 가능.
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Thermo Fisher Scientific LIMK2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the internal part of human LIMK2 (LIM domain kinase 2, LIMK-2) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen is homologous in rat and mouse.
- Specificity: LIMK2.
Target Information
LIMK2 is a serine/threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. It is also implicated in brain development. LIMK2 contains two N-terminal LIM motifs and a C-terminal kinase domain, mediating protein-protein interactions. Activated by ROCK, LIMK2 phosphorylates cofilin, inhibiting actin depolymerization and contributing to Rho-induced cytoskeletal reorganization. Multiple transcript variants exist for LIMK2.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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