Thermo Fisher Scientific Reelin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human Reelin if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Reelin,uniProtId:P78509-1,ncbiNodeId:9606,antigenRange:241-340,antigenLength:3460,antigenImageFileName:PA5-65442_Reelin_P78509-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65442_Reelin_P78509-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663084

Product Specific Information

Immunogen sequence: TFCEPYGPREL ITTGLNTTTA SVLQFSIGSG SCRFSYSDPS IIVLYAKNNS ADWIQLEKIR APSNVSTIIH ILYLPEDAKG ENVQFQWKQE NLRVGEVYE

Highest antigen sequence identity to the following orthologs - mouse 90%, rat 94%.

Target Information

Reelin in an extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.