Thermo Fisher Scientific GLRX Polyclonal Antibody
GLRX 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(Paraffin) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관됩니다. 인간 GLRX에 반응하며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GLRX. Recombinant protein control fragment (Product #RP-104818) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662818 |
Product Specific Information
- Immunogen sequence: IQDYLQQLTGA RTVPRVFIGK DCIGGCSDLV S
- Antigen sequence identity: Highest with mouse (97%) and rat (97%) orthologs.
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs are part of the glutaredoxin system, which includes NADPH, GSH, and glutathione reductase, transferring electrons from NADPH to glutaredoxins via GSH. Initially identified in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase reactions through two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved across species. This 12-kDa dithiol protein plays a role in reducing mixed disulfides in cells exposed to oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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