Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI5D1), TrueMAB
Human KLK8 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, Western blot에 최적화됨. Lyophilized 형태로 제공되며 PBS buffer와 trehalose 포함. 암 연구 및 단백질 발현 분석용 연구 시약으로 적합.
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Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI5D1), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–260 of human KLK8 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological roles. Evidence indicates many kallikreins are involved in carcinogenesis and may serve as biomarkers for cancer and other diseases.
KLK8 is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. The encoded protein may participate in a proteolytic cascade in the skin and act as a biomarker for ovarian cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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