Thermo Fisher Scientific FCER2 Monoclonal Antibody (OTI1E5), TrueMAB
인간 FCER2 단백질을 인식하는 Mouse IgG2b 단일클론 항체. Western blot 및 유세포분석에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. CD23 연구 및 IgE 수용체 관련 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000
- Flow Cytometry (Flow): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 48–321 of human FCER2 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD23 is a 45 kDa glycoprotein expressed on a subset of peripheral blood and tonsil B cells and strongly on EBV-transformed B lymphoblasts. It serves as the low-affinity IgE receptor on B cells. CD23 expression is observed in B cell chronic lymphocytic leukemia and some lymphomas. Functionally, CD23 is involved in B cell growth, differentiation, and IgE production. A soluble form of CD23 acts as a mitogenic factor.
Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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