Thermo Fisher Scientific PIK3CA Monoclonal Antibody (OTI6D9), TrueMAB
PIK3CA 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, 인간 조직에서 반응성이 확인됨. 파라핀 절편 IHC에 적합하며, 동결 건조 상태로 제공. 재구성 시 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 303–631 of human PIK3CA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Phosphatidylinositol 3-kinase consists of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit.
The gene encoding the catalytic subunit (PIK3CA) phosphorylates PtdIns, PtdIns4P, and PtdIns(4,5)P2 using ATP.
This gene is known to be oncogenic and is implicated in cervical cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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