Thermo Fisher Scientific G6PD Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 195-515 of human G6PD (NP_0010358101) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:G6PD,uniProtId:P11413-1,ncbiNodeId:9606,antigenRange:195-515,antigenLength:515,antigenImageFileName:PA5-90417_G6PD_P11413-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90417_G6PD_P11413-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.73 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806063

Product Specific Information

Immunogen sequence: QIYRIDHYLG KEMVQNLMVL RFANRIFGPI WNRDNIACVI LTFKEPFGTE GRGGYFDEFG IIRDVMQNHL LQMLCLVAME KPASTNSDDV RDEKVKVLKC ISEVQANNVV LGQYVGNPDG EGEATKGYLD DPTVPRGSTT ATFAAVVLYV ENERWDGVPF ILRCGKALNE RKAEVRLQFH DVAGDIFHQQ CKRNELVIRV QPNEAVYTKM MTKKPGMFFN PEESELDLTY GNRYKNVKLP DAYERLILDV FCGSQMHFVR SDELREAWRI FTPLLHQIEL EKPKPIPYIY GSRGPTEADE LMKRVGFQYE GTYKWVNPHK L

Positive Samples: MCF7, A-549, NCI-H460, HT-29, K-562, HeLa, 293T, Mouse spleen

Target Information

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.