Thermo Fisher Scientific NOVA1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NOVA1. Recombinant protein control fragment (Product #RP-89051). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NOVA1,uniProtId:P51513-4,ncbiNodeId:9606,antigenRange:328-455,antigenLength:507,antigenImageFileName:PA5-52063_NOVA1_P51513-4_Rabbit.svg,antigenImageFileNamePDP:PA5-52063_NOVA1_P51513-4_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644756

Product Specific Information

Immunogen sequence: NLNTLGLGLS QAAATGALAA AAASANPAAA AANLLATYAS EASASGSTAG GTAGTFALGS LAAATAATNG YFGAASPLAA SAILGTEKST DGSKDVVEIA VPENLVGAIL GKGGKTLVEY QELTGARI

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.