Thermo Fisher Scientific LIMCH1 Polyclonal Antibody
Human LIMCH1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200–1:500 희석으로 사용 가능. 비결합(Unconjugated) 형태이며, 항원 친화 크로마토그래피로 정제됨. Actin 스트레스 섬유 및 세포 이동 조절 연구에 적합.
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Thermo Fisher Scientific LIMCH1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LIMCH1. Recombinant protein control fragment (Product #RP-102346) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643372 |
Product Specific Information
Immunogen sequence:
HTEEVKLIVT CNMRAQESEP VEGGLRKVPD LHKDDLAQQR IQGSLAPHRE PPSFITLSNI TEADLETWER LKVSEKARDG DVQHICASEP SPEIKAETAI RDDFANRKAR ASKKASSPRQ KFVHFGPVTE LDQQKW
Highest antigen sequence identity to the following orthologs:
- Mouse: 22%
- Rat: 24%
Target Information
Actin stress fibers-associated protein that activates non-muscle myosin IIa.
Activates the non-muscle myosin IIa complex by promoting phosphorylation of its regulatory subunit MRLC/MYL9.
Through activation of non-muscle myosin IIa, positively regulates actin stress fiber assembly and stabilizes focal adhesions.
Negatively regulates cell spreading and migration.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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