
Thermo Fisher Scientific Calpain 10 Polyclonal Antibody
인간 Calpain 10 단백질을 표적하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. IHC(P)에서 1:200~1:500 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 PBS 버퍼에 40% 글리세롤 포함, 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific Calpain 10 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Calpain 10. Recombinant protein control fragment (Product #RP-102333). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639241 |
Product Specific Information
Immunogen sequence:
FWLPLLEKVY AKVHGSYEHL WAGQVADALV DLTGGLAERW NLKGVAGSGG QQDRPGRWEH RTCRQLLHLK DQCLISCCVL SPRAGARELG EFHAFIVSDL
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 82%
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that are nonlysosomal and intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large catalytic subunits associated with a common small regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive, and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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