Thermo Fisher Scientific Major Vault Protein (MVP) Monoclonal Antibody (SPM280)
Thermo Fisher Scientific의 MVP 단일클론 항체(SPM280)는 인간 Major Vault Protein을 표적으로 하는 Mouse IgG1 항체입니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능하며, 고순도 Protein A/G 정제 및 PBS buffer로 제공됩니다. 연구용으로만 사용됩니다.
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- 9961MSM2XP1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM280 |
| Immunogen | Proteins precipitated from human breast cancer MCF-7 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
The Major Vault Protein (MVP) gene encodes a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. MVP mediates drug resistance, possibly via a transport mechanism. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells. Overexpression of this protein is a potentially useful marker of clinical drug resistance. This gene produces two transcripts using alternative exon 2 sequences, but both share the same open reading frame.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: 9961-MSM2X-P1ABX_MVP_Q14764-1_House_mouse.svg, 9961-MSM2X-P1ABX_MVP_Q14764-1_House_mouse_PDP.jpeg)
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