Thermo Fisher Scientific TBX1 Monoclonal Antibody (OTI1C2), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

TBX1 is a member of the phylogenetically conserved T-box gene family, which encodes transcription factors that regulate developmental processes.
This gene product shares 98% amino acid sequence identity with the mouse ortholog.
Deletions of chromosome 22q11.2, where TBX1 is located, are associated with DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS), both characterized by neural crest-related developmental defects.
Mouse model studies suggest TBX1 plays a major role in the molecular etiology of DGS/VCFS.
Several alternatively spliced transcript variants encoding different isoforms have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음)