Thermo Fisher Scientific ANKMY2 Monoclonal Antibody (OTI1H4), TrueMAB

Applications

• Western Blot (WB): 1:1,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441-amino-acid protein containing three ANK repeats and one MYND-type zinc finger.
It is encoded by a gene located on human chromosome 7p21.1 and is conserved across multiple species, including chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, and C. elegans.
Downregulation of ANKMY2, often associated with deletions in chromosome 7p22.1, suggests a potential role in the pathogenesis of NK-cell malignancies.
ANKMY2 expression is upregulated by enforced expression of Hox11, which affects hematopoiesis and may promote pre-leukemic states.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.