Thermo Fisher Scientific ANKMY2 Monoclonal Antibody (OTI1H4), TrueMAB
ANKMY2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화됨. HEK293T 세포에서 발현된 full-length human recombinant ANKMY2를 면역원으로 제작. Lyophilized 형태로 제공되며, 재구성 시 1 mg/mL 농도 권장. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H4 |
| Immunogen | Full-length human recombinant ANKMY2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441-amino-acid protein containing three ANK repeats and one MYND-type zinc finger.
It is encoded by a gene located on human chromosome 7p21.1 and is conserved across multiple species, including chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, and C. elegans.
Downregulation of ANKMY2, often associated with deletions in chromosome 7p22.1, suggests a potential role in the pathogenesis of NK-cell malignancies.
ANKMY2 expression is upregulated by enforced expression of Hox11, which affects hematopoiesis and may promote pre-leukemic states.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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