Thermo Fisher Scientific ANKMY2 Monoclonal Antibody (OTI2G1), TrueMAB
Human ANKMY2 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로 Western blot에 적합. 동결건조 형태로 제공되며 PBS buffer와 trehalose 포함. 연구용으로만 사용 가능하며 ANKMY2 관련 NK 세포 질환 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G1 |
| Immunogen | Full length human recombinant protein of human ANKMY2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein containing three ANK repeats and one MYND-type zinc finger.
The gene is located on human chromosome 7p21.1 and is conserved across multiple species including chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, and Caenorhabditis elegans.
Downregulation of ANKMY2, often associated with deletions at chromosome 7p22.1, may contribute to the pathogenesis of natural killer (NK)-cell malignancies.
ANKMY2 expression is upregulated by Hox11, which affects hematopoiesis and promotes pre-leukemic states.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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