Thermo Fisher Scientific Factor V Monoclonal Antibody (5112)
인간 Factor V를 특이적으로 검출하는 단클론 항체로 Western blot 및 RIA에 적합합니다. 마우스 IgG1 형이며, 고농도(8.7 mg/mL) 액상 형태로 제공됩니다. 정제된 인간 Factor V로부터 유래하였으며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 5–10 µg/mL
Radioimmune Assays (RIA)
- Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5112 |
| Immunogen | Purified human factor V |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8.7 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074326 |
Product Specific Information
MA1-43004 detects the human factor Va light chain (fragment E, 74000) and does not react with intact Factor V.
It has been successfully used in RIA and Western blot applications.
Derived from purified human factor V.
Target Information
Coagulation factor V (Proaccelerin) is an essential component of the blood coagulation cascade. It circulates in plasma and becomes activated through thrombin-mediated peptide release during coagulation, generating heavy and light chains held together by calcium ions.
Active factor V acts as a cofactor with activated factor X to convert prothrombin to thrombin.
Defects in the Factor V gene are associated with conditions such as Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, ischemic stroke, and recurrent pregnancy loss.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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