Thermo Fisher Scientific CDK7 Polyclonal Antibody
CDK7 단백질을 인식하는 Goat Polyclonal Antibody로, Western Blot에 최적화되어 있습니다. Human 시료에 반응하며, 고순도 액상 형태로 제공됩니다. Transcription 및 DNA repair 연구에 유용하며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5143233
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HRSEAKDGINRT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933872 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
The trimeric complex of CDK7, cyclin H, and MNAT1 functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, involved in transcription initiation and DNA repair. This complex links transcription regulation and the cell cycle, playing a role in BRCA1-related double-strand break repair. CDK7 may be a target of germline cancer-inducing mutations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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