Thermo Fisher Scientific Phospho-SIN3A (Ser832) Polyclonal Antibody
Phospho-SIN3A (Ser832)에 특이적인 Rabbit Polyclonal 항체로, 인간·마우스·랫트 시료에서 사용 가능. Western blot에 최적화되어 있으며, 내인성 SIN3A의 Ser832 인산화 형태만 검출. 순차 크로마토그래피로 정제된 고순도 액상 항체로 연구용에 적합.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SIN3A (Accession Q96ST3), corresponding to amino acid residues around phosphorylated Ser832 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816536 |
Product Specific Information
Antibody detects endogenous levels of SIN3A only when phosphorylated at Ser832.
Target Information
Mammalian Sin3 (mSin3) is a 150 kDa protein closely related to the yeast SIN3 repressor protein involved in transcriptional repression of many genes. There are two mammalian isoforms, mSin3A and mSin3B.
Both contain four paired amphipathic helix (PAH) domains and interact directly with several transcriptional repressor proteins, including HDAC1, HDAC2, RbAp46, MeCP2, Mad/Max heterodimer, SMRT, and N-CoR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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