Thermo Fisher Scientific PYK2 Polyclonal Antibody
Human PYK2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 1 mg/mL 농도를 유지합니다. 세포 이동 및 MAP kinase 신호전달 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275–325 of Human Protein Tyrosine Kinase 2 beta (PTK2B) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
PTK2B (FAK2) is a cytoplasmic tyrosine kinase involved in calcium-induced regulation of ion channels and activation of the MAP kinase signaling pathway. It regulates actin cytoskeleton reorganization, cell polarization, migration, adhesion, spreading, and bone remodeling. FAK2 is also essential for proper humoral immune response and normal migration of splenic B-cells. Abnormal expression of FAK2 has been associated with tumor proliferation, migration, and invasion, with elevated levels observed in gliomas, hepatocellular carcinoma, lung cancer, and breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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