
Thermo Fisher Scientific Cyp7b1 Monoclonal Antibody (OTI7H10), TrueMAB
인간 Cyp7b1 단백질을 인식하는 마우스 단일클론 항체로 Western blot에 적합. 무보존제, 동결건조 형태이며 재구성 후 1 mg/mL 농도 유지. 콜레스테롤 대사 및 신경스테로이드 연구용으로 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H10 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 350–506 of human Cyp7b1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The CYP7B1 gene encodes a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This endoplasmic reticulum membrane protein initiates the cholesterol catabolic pathway in extrahepatic tissues, converting cholesterol to bile acids.
Although it plays a minor role in total bile acid synthesis, CYP7B1 may be involved in atherosclerosis development, neurosteroid metabolism, and sex hormone synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: CF500244_CYP7B1_O75881-1_House_mouse.svg, CF500244_CYP7B1_O75881-1_House_mouse_PDP.jpeg)
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