Thermo Fisher Scientific PD-L1 Polyclonal Antibody
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA520343 | - | Thermo Fisher Scientific PA520343 PD-L1 Polyclonal Antibody 100 ug pk | 재고문의 | pk | 685,000원 | - | 753,500원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1-2 µg/mL
View 11 publications 11 publications
Immunohistochemistry (IHC)
-
View 11 publications 11 publications
Immunohistochemistry (Paraffin) (IHC (P))
10 µg/mL
View 2 publications 2 publications
Immunocytochemistry (ICC/IF)
1:100
View 2 publications 2 publications
Flow Cytometry (Flow)
0.5 µg/mL
View 3 publications 3 publications
Immunoprecipitation (IP)
-
View 1 publication 1 publication
Functional Assay (Functional)
-
View 1 publication 1 publication
Immunomicroscopy (IM)
-
View 1 publication 1 publication
Product Specifications
Species Reactivity
Human, Mouse, Rat
Published species
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 17 amino acid peptide from near the center of human PDL-1.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice (domestic); Dry ice (international)
RRID
AB_11153819
Product Specific Information
This antibody detects human PD-L1 isoform 1 (290aa, 33.3 kDa) and isoform 3 (178aa, 20.5 kDa), as well as mouse and rat PD-L1 (290aa, 33 kDa). It will not cross-react with PD-L2. By Western blot, this antibody has been observed to detect a band at 37 kDa.
Recommended positive controls: HeLa cell lysate, Daudi cell lysate, K562 cell lysate, human heart tissue/lysate.
PA5-20343 can be used with blocking peptide PEP-0463.
The PA5-20343 immunogen is located within amino acids 60-110 of PD-L1.
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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