Thermo Fisher Scientific BAX Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 Bax 단백질(aa 1-100)을 인식. Western blot 및 Immunoprecipitation에 적합. 세포 사멸 조절 연구용으로 사용. 액상 형태, -20°C 보관, RRID: AB_2913698.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–100 of human Bax (NP_620116.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913698 |
Product Specific Information
- Positive test controls: HeLa, MCF-7, HT-1080
- Localization: Cytoplasm, Mitochondrion membrane, Single-pass membrane protein
Immunogen sequence:
MDGSGEQPRG GGPTSSEQIM KTGALLLQGF IQDRAGRMGG EAPELALDPV PQDASTKKLS ECLKRIGDEL DSNMELQRMI AAVDTDSPRE VFFRVAADMF
Target Information
BAX is a member of the Bcl-2 family and plays an important role in regulating apoptosis.
While Bcl-2 acts as an anti-apoptotic protein, BAX promotes apoptosis.
Regulation involves homo- and heterodimerization of BAX and Bcl-2 isoforms.
The Bax gene encodes isoforms Bax alpha (21 kDa) and Bax beta (24 kDa), both containing BH1, BH2, and BH3 domains.
Bax beta has a unique carboxyl terminus lacking a hydrophobic transmembrane domain.
Overexpression of BAX promotes cell death through dimerization with BCL-2 family proteins.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(PA5-120126_BAX_Q07812-1_Rabbit.svg 및 PA5-120126_BAX_Q07812-1_Rabbit_PDP.jpeg 이미지 참조)
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