Thermo Fisher Scientific BTK Monoclonal Antibody (OTI6H9), TrueMAB
BTK 단백질을 표적으로 하는 Mouse monoclonal antibody로 Western blot, IHC, ICC, Flow cytometry에 적합합니다. 고순도 Affinity chromatography 정제 및 안정적인 PBS/BSA/glycerol buffer로 보관됩니다. 연구용으로만 사용됩니다.
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- TA501093
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6H9 |
| Immunogen | Full length human recombinant BTK protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily. Mutations in the BTK gene are associated with severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. BTK interacts with toll-like receptor (TLR) family members including TLR4, 6, 8, and 9, which are key components of innate and adaptive immunity. It has also been shown to interact with MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting a role in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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