Thermo Fisher Scientific IRF4 Monoclonal Antibody (01)
IRF4 단백질을 인식하는 Thermo Fisher Scientific의 Mouse monoclonal 항체입니다. 인간 시료에 반응하며 Flow Cytometry에 적합합니다. Protein A로 정제된 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관을 권장합니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 01 |
| Immunogen | A synthetic peptide corresponding to the center region of the Human Irf4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866578 |
Product Specific Information
This antibody reacts with Human and Mouse (species predicted to react based on 100% sequence homology).
Target Information
The IRF (interferon regulatory factor) family of transcription factors are characterized by a unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to viral infection and in the regulation of interferon-inducible genes.
IRF4 is lymphocyte-specific and negatively regulates toll-like receptor (TLR) signaling, which is central to the activation of innate and adaptive immune systems.
A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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